NCT04658290招募中不适用
Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 500
- 试验地点
- 1
- 主要终点
- Number of subjects having apnea-hypopnea index of more than 5
研究概览
简要总结
The study is aimed to carry out an epidemiology study investigating the prevalence of obstructive sleep apnea (OSA) and the association with cognitive impairment.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 40 Years 至 74 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Have stability of at least 4 weeks on permitted medications (i.e. medications known not to affect sleep architecture or circadian rhythms).
排除标准
- •Suspected dementia or a score of <24 on the mini-mental state examination
- •A diagnosis of neurological disorders (e.g. Parkinson's Disease, Epilepsy, Multiple Sclerosis)
- •Psychiatric disorders including current major depression; bipolar disorder; schizophrenia
- •Other known clinically significant sleep disorders (e.g. narcolepsy)
- •Been currently receiving CPAP or bi-level pressure for OSA
结局指标
主要结局
Number of subjects having apnea-hypopnea index of more than 5
时间窗: 1 year
次要结局
- incidence of cerebrovascular disease(5 years)
- Montreal Cognitive Assessment(5 years)
研究者
Susanna SS Ng
Assistant Professor
Chinese University of Hong Kong
研究点 (1)
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