Pre-procedure Planning for Radiofrequency Ablation Using the Automatic Fusion Images of the Registrated 3D CT or MR-US Scans: Preliminary Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 240
- 试验地点
- 1
- 主要终点
- RFA feasibility rates on planning USG with/without fusion CT/MR and US
研究概览
简要总结
The purpose of this study is to determine whether fusion technique of pre-radiofrequency ablation (RFA) cross-sectional imaging (CT or MR) and real-time ultrasonography would improve feasibility of RFA in patients with liver tumor in comparison with ultrasonography guidance alone.
详细描述
RFA is one of commonly used local therapies for primary or secondary liver tumors. For successful and safe procedure, safe route of electrode and lesion visibility are essential for RFA, and the conditions are usually evaluated on pre-RFA planning ultrasonography (USG). However, RFA is sometimes aborted due to limited sonic window of various cause and challenging identification of small isoechoic tumors or hepatocellular carcinomas among dysplastic nodules . Therefore, precise targeting and assuring safe route would be of clinical importance. In this preliminary study, investigators attempted to determine US and CT/MR fusion technique would be able to improve RFA feasibility in patients with liver tumors in comparison with conventional US alone technique.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •all conditions should be satisfied for inclusion.
- •referred to Radiology in our institution for liver tumor RFA
- •available pre-RFA liver CT or liver MR imaging within 6 weeks
排除标准
- •patients with any of following condition should be excluded.
- •any contraindication of liver RFA
- •any patients who received treatment between pre-RFA imaging and planned RFA
- •patients referred for palliative purpose.
结局指标
主要结局
RFA feasibility rates on planning USG with/without fusion CT/MR and US
时间窗: 10 minutes after finishing planning USG
comparison of rates of RFA feasibility on conventional planning USG and on fusion planning USG
次要结局
- Number of patients with safety access route on planning USG with/without fusion technique(10 minutes after finishing planning USG)
- Rate of tumor visibility on planning USG with/without fusion technique(10 minutes after finishing planning USG)
研究者
Jeong Min Lee
Professor
Seoul National University Hospital