NCT03942237已完成不适用
Transmuscular Quadratus Lumborum Block for Postoperative Pain After Laparoscopic Adrenalectomy
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 72
- 试验地点
- 1
- 主要终点
- the NRS pain scores on activity 12-hours after surgery
研究概览
简要总结
This prospective, randomized control study aims to compare the analgesic effect, satisfaction with anesthesia and analgesia between single-injection QLB (quadratus lumborum block)+general anesthesia (GA) and general anesthesia (GA) alone in patients undergoing laparoscopic adrenalectomy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-70 yrs
- •American Society of Anesthesiologists physical statusⅠ-Ⅲ
- •Undergo laparoscopic adrenalectomy
- •Informed consent
排除标准
- •a known allergy to the medications being used for anesthesia
- •coagulopathy or on anticoagulants
- •chronic opioid therapy or history of substance abuse
- •participating in another RCT
- •inability to properly describe postoperative pain to investigators (e.g., language barrier, neuropsychiatric disorder).
研究组 & 干预措施
single-injection QLB (quadratus lumborum block)
Experimental
Single-injection of QLB with local anesthetic is given preoperatively
干预措施: single-injection QLB(quadratus lumborum block) (Procedure)
Placebo control
Placebo Comparator
Single-injection of QLB with NS is given preoperatively
干预措施: Placebo Control (Procedure)
结局指标
主要结局
the NRS pain scores on activity 12-hours after surgery
时间窗: 12-hours after surgery
The NRS (a number scale from 0 to 10) is a commonly used pain intensity rating tool
次要结局
- postoperative length of hospital stay(up to 2 weeks after surgery)
- the pain scores at rest determined by the numeric rating scale (NRS, 0-10)(At 2,4, 8, 12, 24 ,48,72 hours after the surgery)
- time of recovery of bowel movement(within 5 days after surgery)
- the NRS pain scores on activity after surgery(At 2,4, 8, 24 ,48,72 hours after the surgery)
- incidence of postoperative nausea and vomiting (PONV)(within 24 postoperative hours)
- patient's satisfaction of anesthesia and analgesia(48 hours after surgery)
- ambulation time(within 5 days after surgery)
研究者
Cui Xulei
Attending physician
Peking Union Medical College Hospital
研究点 (1)
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