Acute Food INtake Effect of Hemp Protein (A FINEH Protein) Trial - Part 2 - Are Acute Effects of Hemp Protein on Blood Glucose and Appetite Insulin-dependent?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 15
- 试验地点
- 2
- 主要终点
- Plasma Glucose and Insulin Concentrations
研究概览
简要总结
The objectives of this trial are to investigate whether the effects of hemp protein on glycemic and appetite control are insulin-dependent by measuring 1) blood glucose, insulin and appetite for one hour following consumption, 2) blood glucose, insulin and appetite following a fixed energy meal to determine the "second meal effect" of hemp protein versus soybean protein and a non-protein control.
详细描述
The objectives of this trial are to investigate whether the effects of hemp protein on glycemic and appetite control are insulin-dependent by measuring 1) blood glucose, insulin and appetite for one hour following consumption, 2) blood glucose, insulin and appetite following a fixed energy meal to determine the "second meal effect" of hemp protein versus soybean protein and a non-protein control. The objectives of this trial are to investigate whether the effects of hemp protein on glycemic and appetite control are insulin-dependent by measuring 1) blood glucose, insulin and appetite for one hour following consumption, 2) blood glucose, insulin and appetite following a fixed energy meal to determine the "second meal effect" of hemp protein versus soybean protein and a non-protein control.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Normoglycemic (<5.6 mmol/L)
- •Body mass index (BMI) of 18.5-29.9 kg/m2.
排除标准
- •Restrained eaters
- •Regularly skip breakfast
- •Those on medications that may influence study outcomes or have experienced any gastrointestinal related health conditions/surgeries over the past year.
结局指标
主要结局
Plasma Glucose and Insulin Concentrations
时间窗: 0-200 minutes
Measured in blood using intravenous catheter at 12 time points, used to calculate area under curve (AUC). Glucose will be determined by automated methods using Abbot Spectrum CCX Analyzer, and Insulin will be measured by commercially available RIA kits. (Composite measure)
Food Intake
时间窗: 0-200 minutes
Measured by fixed energy meal.
Blood Pressure
时间窗: 0-200 minutes
Measured by automated bood pressure cuff.
Appetite
时间窗: 0-200 minutes
Measured by VAS Questionnaire.
次要结局
- Palatability of Treatments and Meal(5-80 minutes)
- Physical Comfort(0-200 minutes)
- Energy/Fatigue(0-200 minutes)