NL-OMON35323已完成不适用
Discovering the Dynamics of Endothelial Shear Stress - DISCOVER
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1) Healthy individuals aged between 18 and 45 years old.
- •2) Not known with any clinical significant disease
- •3) Not using any prescription medication
- •4) Non-smoking
- •1) Patients aged equal to or greater than (*) 45 years.
- •2) Known with an elevated LDL cholesterol (LDL > 90th percentile) with or without LDLc lowering therapy
排除标准
- •Group A and B: ;1) Current active inflammatory diseases.
- •2) Any clinically significant medical condition that could interfere with the conduct of the study.
- •3) Known with hypertension (>15 years) , cardiac hypertrophy, cardiac failure (NYHA class I-IV) or any form of ischemic heart disease.
- •4) Standard contra-indications to MRI.
- •5) Inability or unwillingness to comply with the protocol requirements, or deemed by investigator to be unfit for the study.
- •6) Contra-indications to salbutamol and / or nitroglycrine;For group A only:
- •1) Previous clinical significant vaccination reactions
研究者
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