A double blind randomized control study to compare the antiemetic efficacy of ondansetron versus ondansetron and dexamethasone combination in patients undergoing breast surgeries.

Serotonin (5 Hydroxy tryptamine) receptor antagonists like ondansetron are the most commonly used drug for the prevention and treatment of Post-Operative nausea and vomiting (PONV) in all surgeries.

It has been found that there is a very high incidence of PONV in patients undergoing breast surgeries.

It has been found that the glucocorticoid, dexamethasone is a very potent and long acting anti emetic and it also augments the antiemetic property of other drugs.

Thus in our study we are comparing the efficacy of ondansetron alone or when used in combination with dexamethasone is better for preventing PONV and need for rescue antiemetic in patients undergoing breast surgeries.