DRKS00003350招募中不适用
Endophenotyping in alcoholic patients with glutamate spectoscopy: Genetic modulation and treatment response
Zentralinstitut für Seelische GesundheitKlinik für Abhängiges Verhalten und Suchtmedizin0 个研究点目标入组 320 人开始时间: 2011年12月12日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 320
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •Men and women aged 18 to 65
- •- Legally effective, written informed consent for participation within the study
- •Alcohol dependent subjects:
- •- Diagnose of alcohol dependence according to ICD-10 and DSM-IV
- •Healthy controls:
- •- no or minimal consumption of alcohol,
- •- laboratory parameters sensitive for alcohol within normal range,
排除标准
- •- Actual psychiatric disorder (Axis I) according to DSM-IV / ICD-10 (assessed with SCID-I) except nicotine abuse or nicotine dependence and alcohol dependence for patients
- •- Positive drugscreen (opiates, cannabinoids, benzodiazepines, barbiturates, cocaine, amphetamine),
- •- actual treatment with psychoactive medication,
- •- MR contraindication (e.g. pacemaker, metallic or electronic implants, metal splinters…)
- •- Severe physical disorders (liver-cirrhosis, severe diabetes),
- •- former psychotic disorder,
- •- actual suicidal tendency or endangerment of others
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