Postoperative Sleep Quality of Patients Anesthesia With Propofol or Sevoflurane Undergoing Thyroidectomy
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 124
- 试验地点
- 1
- 主要终点
- The Change of postoperative sleep quality
研究概览
简要总结
The investigators designed a study to determine whether Propofol or Sevoflurane would provide same postoperative sleep quality in patients undergoing thyroidectomy.
详细描述
The investigators designed a study to determine whether Propofol or Sevoflurane would provide same postoperative sleep quality in patients undergoing thyroidectomy.The bispectral index score (BIS) was monitored during the operation and the first postoperative night.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Participants were deemed eligible if they were candidates for general anesthesia undergoing thyroidectomy
排除标准
- •Patients were excluded if they had a body mass index exceeding 30 kg/m2, had a Pittsburgh Sleep Quality Index global scores higher than 6, had an anesthesia time longer than 4 hours, had a history of cardiovascular, neurological, or psychiatric disease, had cervical lymph node metastasis, were treated with sedative and analgesics during the postoperative BIS-Vista monitoring period, were allergic to drugs used in the study, or had been diagnosed with Graves' disease or hyperthyroidism or hypothyroidism.
研究组 & 干预措施
Propofol
introvenious infusion of propofol
干预措施: propofol (Drug)
Inhaled anaesthetic (Sevoflurane)
sevoflurane (1.0-1.3% Minimum Alveolar Concentration)
干预措施: sevoflurane (Drug)
结局指标
主要结局
The Change of postoperative sleep quality
时间窗: preoperation, first postoperative night
The primary outcome was the postoperative sleep quality, which was measured by the BIS-Vista monitor on the first night after surgery.
次要结局
未报告次要终点
研究者
Wen-fei Tan
Associate Professor
China Medical University, China