Effect of Propofol and Sevoflurane on Postoperative Catheter-Related Bladder Discomfort
Overview
- Phase
- Not Applicable
- Intervention
- Propofol
- Conditions
- Catheter Site Discomfort
- Sponsor
- Seoul National University Hospital
- Enrollment
- 82
- Locations
- 1
- Primary Endpoint
- Catheter-related Bladder Discomfort
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.
Detailed Description
The mechanism of catheter-related bladder discomfort is thought to be related to the muscarinic receptor. Propofol and desflurane are most widely used as an anesthetic agent. Propofol and desflurane are known to block the muscarinic receptor in different ways. The investigators want to evaluate the efficacy of the propofol and sevoflurane for the prevention of catheter-related bladder discomfort.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patients scheduled for transurethral bladder excision under general anesthesia
- •ASA I-III
Exclusion Criteria
- •Foley catheter less than 18 Fr.
- •Patients with obstruction of urinary tract
- •Patients with neurogenic bladder
- •Patients with severe obesity
- •Patients with neurologic disorder
- •Patients with chronic pain
- •Patients with allergic history to propofol or sevoflurane
Arms & Interventions
Propofol
Propofol will be administered as the anesthetic maintenance agent.
Intervention: Propofol
Sevoflurane
Sevoflurane will be administered as the anesthetic maintenance agent.
Intervention: Sevoflurane
Outcomes
Primary Outcomes
Catheter-related Bladder Discomfort
Time Frame: 1 hour postoperatively
Catheter-related bladder discomfort will be measured at 1 hour postoperatively (0:none, 1:mild, 2:moderate, 3:severe). Patients with score \>0 will be counted.
Secondary Outcomes
- Blurred Vision(0, 1, 6 and 24 hour postoperatively)
- Dry Mouth(0, 1, 6 and 24 hour postoperatively)
- Flushing(0, 1, 6 and 24 hour postoperatively)
- Dizziness(0, 1, 6 and 24 hour postoperatively)
- Catheter-related Bladder Discomfort(0, 6 and 24 hour postoperatively)
- Hemodynamic Parameters(0, 1, 5, 10 minute postoperatively)
- Nausea(0, 1, 6 and 24 hour postoperatively)
- Vomiting(0, 1, 6 and 24 hour postoperatively)
- Analgesics(0, 1, 6 and 24 hour postoperatively)