DRKS00027324招募中不适用
Vaccination and the human intestinal microbiome - µHEAT
Department of Microbiome ScienceMax Planck Institute for Developmental BiologyEberhards Karls University of Tubingen0 个研究点目标入组 256 人开始时间: 2022年7月7日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 256
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 40 Years（—）
- 性别
- All
入选标准
- •Participants must be adults 18-40 years of age, with no underlying health conditions, belonging to the Robert Koch priority group 4 (de-prioritized for vaccination). Participants must intend to be vaccinated against COVID-19 and be able to receive their vaccination during the study timeline (~Sept 2021-Dec 2022). Any of the COVID-19 vaccinations approved by the Robert Koch Institute at the time of study participation (e.g., BioNTech/Pfizer, Moderna, Johnson & Johnson or other commercially available vaccines) will be permitted for inclusion in the study, including booster shots. Participants must be able to read and understand German or English to provide informed consent for themselves.
排除标准
- •Exclusion criteria include known gastrointestinal disorders (e.g., Inflammatory Bowel Disease or Celiac Disease), recent antibiotics use (any antibiotics taken in the three months prior to study participation), and pregnancy. Any health factor which places someone at higher risk of COVID-19 disease, and therefore in a higher vaccine priority group (1-3) according to the Robert Koch Institute will also be excluded. These exclusion risk factors, as listed by the Robert Koch Institute, include diabetes mellitus, obesity (BMI>30), asthma, autoimmune diseases, neurological diseases, cancer, and diseases of the lung, heart, liver, or kidney. Immunocompromised and immunosuppressed people are also explicitly excluded.
- •However, healthy individuals who receive vaccine prioritization for occupational reasons (for example, researchers working at the hospital campus) are not excluded from the study.
研究者
相似试验
已完成
不适用
Vaccination and the human intestinal microbiome (µHEAT)DRKS00032373Max Planck-Institut187
已完成
不适用
The influence of the gut microbiome on immunity mediated by COVID-19 vaccinatiohealthy volunteersDRKS00027050Institut für Prävention und Tumorepidemiologie143
已完成
不适用
The Role of the Intestinal Microbiome in Enteric and Systemic Vaccine Immune ResponsesRotavirus InfectionsIntestinal Bacteria Flora DisturbanceReaction - Vaccine NosStreptococcal PneumoniaTetanusNCT02538211Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)63
已完成
不适用
Impact of intestinal microbiome on infections, course and outcome of haematological-oncological patients treated with chemotherapygut microbiomeC92.0Acute myeloblastic leukaemia [AML]DRKS00011674niversitätsklinikum Magdeburg12
已完成
不适用
Role of the immune system and the gut microbiota in neuroprotection: a dietary human intervention trialcardio metabolic riskDRKS00015861Institut für Ernährungs- und Lebensmittelwissenschaften, Abteilung Ernährungsphysiologie, Rheinische Friedrich-Wilhelms-Universität Bonn120