Effect of Myopic Femtosecond Laser Asssisted-LASIK on Anaterior Chamber Flare Values and Corneal Endothelial Cells
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Change of Flare Values
研究概览
简要总结
This study aimed to investigate whether femtosecond laser-assisted LASIK (FS-LASIK) surgery causes inflammation in the anterior chamber and to analyze its effect on endothelial cells.
详细描述
Since FS-LASIK surgery is applied using both an FS laser and an excimer laser, we aimed to determine the direct and indirect effects of these applications on the corneal endothelium, the intensity of the inflammation, and the blood-aqueous barrier in the anterior chamber. To the best of our knowledge, the effects of FS-LASIK on anterior chamber inflammation have not been previously investigated. Therefore, we evaluated these effects using objective measurement methods, such as specular microscopy and laser flare photometry.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Prevention
- 盲法
- None
盲法说明
Patients name and identifiers were masked
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •The patients who performed Femtosecond laser assisted LASIK for myopia or myopic astigmatism.
- •Uncomplicated surgery
排除标准
- •Complicated surgery,
- •Hyperopic or hyperopic astigmatism
- •Lack of follow-up measurements
结局指标
主要结局
Change of Flare Values
时间窗: The change of flare values on first day, seventh day, 1. month and 3. months according to preoperative values
To measure anterior chamber inflammation objectively, Flare values were measured by the laser flare-photometry
次要结局
- Change of Corneal endothelium features-1(the changes of the parameters of preoperative and 3. months' values)
研究者
Kemal Turgay Ozbilen
M.D. Academics
Istanbul University