跳至主要内容
临床试验/NCT04609605
NCT04609605Unknown不适用

Assessment of Right Ventricular Function After Acute Pulmonary Embolism Using Speckle Tracking Echocardiography

Assiut University0 个研究点目标入组 68 人开始时间: 2020年12月最近更新:
适应症

试验速览

阶段
不适用
入组人数
68
主要终点
improve management of acute pulmonary embolism

研究概览

简要总结

  1. To asses regional RV function in patients presented with acute pulmonary embolism using speckle tracking echocardiography
  2. To evaluate its relationship to long term mortality.

详细描述

Pulmonary embolism (PE) is the third most common cardiovascular cause of death after myocardial infarction and stroke . The incidence of PE has been increasing ,with significant associated mortality; a recent registry of PE patients reported a mortality rate > 10% at 30 days. There are a number of emerging contemporary PE therapies, including thrombolysis, catheter intervention and surgery. Early and accurate identification of PE in patients is therefore critical. A transthoracic echocardiogram (TTE) may help when there is a clinical suspicion for PE, and its use in confirmed PE is widely recommended . A number of right atrial (RA) and right ventricular (RV) parameters have been shown to be abnormal in patients with PE . In addition, RA and RV enlargement portends a worse prognosis in these patients .

研究设计

研究类型
Interventional
分配方式
Na
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
20 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • clinical diagnosis of acute pulmonary embolism
  • Age: 20 - 70 years.

排除标准

  • coronary artery disease
  • patient of Atrial fibrillation.
  • Patient of impaired RV function due to chest disease (Cor-pulmonale)
  • patient with impaired Ejection fraction (EF) <50%
  • Moderate to severe valvular heart disease.
  • Atrio-ventricular conduction disturbance.
  • Poor echogenicity

结局指标

主要结局

improve management of acute pulmonary embolism

时间窗: baseline

comparison between speckle tracking echocardiograpgy and conventional echocardiography in pulmonary embolism

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Mahmoud Said Rashwan

doctor

Assiut University

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