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临床试验/NCT06803212
NCT06803212已完成不适用

Effect of Dual-Task Interference on Upper Extremity Motor Experience With Parkinson's Disease

Emre Şenocak1 个研究点 分布在 1 个国家目标入组 32 人开始时间: 2024年6月28日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
32
试验地点
1
主要终点
Movement Disorder Society (MDS)-Unified Parkinson's Disease Rating Scale (MDS-UPDRS):

研究概览

简要总结

This study was conducted to investigate the effects of dual-task training on upper extremity motor functions in patients with Parkinson's disease. A total of 32 patients participated in the study. Patients were divided into two groups by randomization. One group received only conventional physiotherapy applications, while the other group performed dual-task exercises in addition. Dual-task exercises were performed while conventional treatment was applied. The treatment program was applied as 60x5x6 min/day/week.

Conventional treatment was determined according to the individual needs of the patients, including the lower and upper extremities. Dual-task interventions included performing such as counting backward, word recall, and reading words backward.

Assessments were repeated twice: Baseline and after a 30-session. "Demographic Information", "Movement Disorder Society (MDS)-Unified Parkinson's Disease Rating Scale (MDS-UPDRS)", "Box and Block Test" and "Parkinson Disease Questionnaire (PDQ-39) were used as assessment tools.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
None

入排标准

年龄范围
50 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者
否

入选标准

  • •Patients aged 50-85 years with a diagnosis of Stage 1-3 Parkinson's disease, based on the Hoehn & Yahr Scale
  • •Patients had to have no issues with performing basic mathematical operations, - A Mini-Mental State Examination (MMSE) score above 24 points,
  • •Regular medication use for at least 4 weeks (for patients who were prescribed medical treatment),
  • •No comorbid neurological, neuromuscular, or orthopedic diseases

排除标准

  • •Patients with vision or hearing impairments,
  • •Moderate-to-severe fluctuations in tremor or dyskinesia,
  • •Having deep brain stimulator implants, or sensory loss in the upper extremities.

研究组 & 干预措施

Conventional Therapy

Active Comparator

This group were performed just conventional physiotherapy.

干预措施: Conventional Physiotherapy Program (Other)

Dual-Task Interference

Experimental

Dual-task exercises were applied during conventional physiotherapy practices.

干预措施: Conventional Physiotherapy Program (Other)

Dual-Task Interference

Experimental

Dual-task exercises were applied during conventional physiotherapy practices.

干预措施: Dual-Task Interference (Other)

结局指标

主要结局

Movement Disorder Society (MDS)-Unified Parkinson's Disease Rating Scale (MDS-UPDRS):

时间窗: End of the 30th physiotherapy session

The scale consists of four separate domains. The first section includes non-motor experiences in daily life (13 items), the second section includes motor experiences in daily life (13 items), the third section involves motor examination (33 items), and the last section addresses motor complications (6 items). The scale contains 65 individual items in total. Items are generally scored between 0-4, with some Yes/No items. The domains of the scale directly related to the upper extremities, including eating, dressing, cleaning, writing, rigidity, finger movements, hand movements, pronation and supination of the hand, postural tremor in the hands, kinetic tremor in the hands, resting tremor, and tremor persistence, were used in this study (Figure 1). The MDS-UPDRS scoring was performed while patients were in the "ON" state.

Movement Disorder Society (MDS)-Unified Parkinson's Disease Rating Scale (MDS-UPDRS):

时间窗: Baseline of the study

The scale consists of four separate domains. The first section includes non-motor experiences in daily life (13 items), the second section includes motor experiences in daily life (13 items), the third section involves motor examination (33 items), and the last section addresses motor complications (6 items). The scale contains 65 individual items in total. Items are generally scored between 0-4, with some Yes/No items. The domains of the scale directly related to the upper extremities, including eating, dressing, cleaning, writing, rigidity, finger movements, hand movements, pronation and supination of the hand, postural tremor in the hands, kinetic tremor in the hands, resting tremor, and tremor persistence, were used in this study (Figure 1). The MDS-UPDRS scoring was performed while patients were in the "ON" state.

次要结局

  • Box Block Test (BBT)(End of the 30th physiotherapy session)
  • Parkinson's Disease Questionnaire - 39 (PDQ-39)(End of the 30th physiotherapy session)
  • Demographic Data Form(Baseline of the study)
  • Box Block Test (BBT)(Baseline of the study)
  • Parkinson's Disease Questionnaire - 39 (PDQ-39)(Baseline of the study)

研究者

发起方
Emre Şenocak
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Emre Şenocak

Assistant Professor (PhD)

Karadeniz Technical University

研究点 (1)

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