NCT02867488已完成不适用
Dose-response Effects of Soybean Oil in Salad Dressing on Carotenoid/Fat-soluble Vitamin Bioavailability in Salad Vegetables
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 主要终点
- Area under the curve for carotenoids, phylloquinone, tocopherols, and retinyl palmitate in the plasma chylomicron fraction
研究概览
简要总结
The objectives will be to evaluate the dose-response between the amount of soybean oil in salad dressing and the absorption of: 1) carotenoids, phylloquinone, and tocopherols in salad vegetables; 2) retinyl palmitate formed from the provitamin A carotenoids, alpha- and beta-carotene.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •General good health as determined by interview, blood biochemistry profile, complete blood count, and plasma lipid and lipoprotein profile
排除标准
- •Cigarette smoking, frequent alcohol consumption
- •Use of vitamin/mineral supplements
- •Lactose intolerance
- •Known food allergies
- •Body mass index (BMI) 30 or higher
- •Eating disorder or restrained eating
- •Vegetarianism
- •Hyperlipidemia
- •Current or planned pregnancy
- •Use of hormonal contraceptives (affects chylomicron clearance); use of plant sterols or medications known to affect lipid metabolism
结局指标
主要结局
Area under the curve for carotenoids, phylloquinone, tocopherols, and retinyl palmitate in the plasma chylomicron fraction
时间窗: 0-9.5 hours postprandially
次要结局
未报告次要终点
研究者
Wendy S. White
Associate Professor
Iowa State University
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