Metabolic Effects of One-Week Heavy Drinking and Fast Food Intake During Roskilde Festival in Young Healthy Male Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 28
- 主要终点
- Impairment of glucose tolerance
研究概览
简要总结
Examination of the effect of one week's unhealthy lifestyle on glucose metabolism and liver parameters in a group of young, healthy males participating in Roskilde Festival 2016.
详细描述
Metabolic effects of intermittent unhealthy lifestyle in otherwise young healthy adults are poorly studied. The investigators evaluated the effect of one week's unhealthy lifestyle on glucose metabolism and liver parameters in a group of young, healthy males participating in Roskilde Festival 2016.
Festival participants were studied before and after participation (one week) in Roskilde Festival 2016 and matched with controls who lead a normal life for an equivalent period of time. An oral glucose tolerance test (OGTT), abdominal ultrasound and strain elastography for liver stiffness were performed together with a bioimpedance scan and cognitive tests.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 30 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •BMI of 18,5-25 kg/m2
- •Normal liver function (assessed by ASAT, ALAT, GGT, alkaline phosphatase, albumin and bilirubin, coagulation factors II, VII and X, INR and platelets)
排除标准
- •Planning alcohol withdrawal or dieting/a special low-fat diet during Roskilde Festival
- •Diabetes or pre-diabetes
- •First degree relatives with diabetes
- •Kidney disease (eGFT<60 ml/min and/or albuminuria)
- •Chronic diseases (in addition to those already mentioned) that could affect participation in festival activities (concerts and parties)
- •Any condition in which the investigator believed would make it impossible to participate
结局指标
主要结局
Impairment of glucose tolerance
时间窗: First day after intervention week
Evaluated by OGTT
次要结局
- Hepatic steatosis(First day after intervention week)
研究者
Filip Krag Knop
Professor, MD, PhD
University Hospital, Gentofte, Copenhagen