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临床试验/NCT01897350
NCT01897350已完成不适用

Myocardial Oedema in ST Segment Elevation Myocardial Infarction Myocardial

Elisa McAlindon1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2013年7月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
30
试验地点
1
主要终点
The mass of myocardial oedema measured by CMR

研究概览

简要总结

Cardiac magnetic resonance imaging (CMR) is a non invasive technique used to obtain functional and anatomical information on the heart. Several CMR parameters measured after primary percutaneous coronary intervention (PPCI) have been shown to have prognostic value and are increasingly being used as surrogate endpoints in clinical trials. Myocardial oedema is a prognostic indicator following myocardial infarction1. Myocardial salvage is calculated as the myocardial oedema minus infarct size; this again is a prognostic indicator following STEMI. However, myocardial oedema imaging is controversial. There are multiple sequences available, with no standardisation of sequences used to assess this surrogate endpoint. The investigators propose to conduct a study to measure the myocardial oedema by all available techniques to determine the agreement between these methods.

研究设计

研究类型
Observational
时间视角
Prospective

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • providing written informed consent

排除标准

  • contraindication to CMR,
  • atrial fibrillation,
  • claustrophobia,
  • eGFR < 30

结局指标

主要结局

The mass of myocardial oedema measured by CMR

时间窗: Day 2 following STEMI

次要结局

  • Extra cellular volume(Day 2 following STEMI)

研究者

发起方
Elisa McAlindon
申办方类型
Other
责任方
Sponsor Investigator
主要研究者

Elisa McAlindon

principle investigator

University of Bristol

研究点 (1)

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