EUCTR2013-001685-42-DK进行中（未招募）不适用
Changes in coagulation and platelet reactivity in HIV-1 infected patients switching between abacavir and tenofovir containing antiretroviral regimens - TAPAS
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- Male
入选标准
- •HIV-1 infected
- •Can understand and sign written informed consent
- •Between 35 and 70 years old at inclusion
- •Received one of the above mentioned antiretroviral regimens continuously = 6 months
- •HIV RNA < 400 copies/mL for = 6 months
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range 80
- •F.1.3 Elderly (>=65 years) yes
- •F.1.3.1 Number of subjects for this age range 20
排除标准
- •Receiving anticoagulant therapy, ADP-receptor inhibitors, aspirin or NSAIDs
- •Previous ischemic heart disease, peripheral atherosclerotic disease or stroke
- •Coagulation disorder (e.g. hemophilia, factor V Leiden mutation)
- •Platelet count < 150 x 109/L during the past 6 months from inclusion
- •eGFR<70 during the past 6 months from inclusion
- •HLA-B*57:01 positive genotype
- •Hepatitis B or C positive during the past year from inclusion
研究者
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