Comparative study of effectiveness between 20% azelaic acid with low-fluence 1064-nm Nd:YAG picosecond laser and 20% azelaic acid alone in the treatment of melasma in Thai female patients, split-face, prospective study

Institute of Dermatology, Bangkok, Thailand0 个研究点目标入组 20 人开始时间: 2023年1月12日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1)Thai female patients
•2)Aged 18-65 years old
•3)Diagnosed with bilateral symmetrical malar type melasma at the face
•4)Can be able to attend and willing to be a subject in this study including being able to give a consent

•1)Taking oral contraceptive pills or receiving hormone replacement
•2)In the period of pregnancy or lactation
•3)Have underlying disease of autoimmune diseases such as SLE
•4)Have underlying disease of thyroid diseases
•5)Allergy to azelaic acid or preservatives in topical melasma treatment
•6)Have a laser treatment on the face within 6 months before the study
•7)Using topical melasma treatments such as kojic acid, hydroquinone, alpha arbutin and whitening agents within 4 weeks before the study
•8)Treated melasma by chemical peeling agents within 3 months before the study
•9)Using tranexamic acid or vitamin C within 3 months before the study
•10) Taking or applying retinoid within 12 months before the study
•11) Having an active asthma
•12) Having a history of using antiepileptic drugs
•13) Having skin infections or any other skin disease, for example, allergic dermatitis, cellulitis, erysipelas, herpes simplex and herpes zoster infection on the face

发起方

Institute of Dermatology, Bangkok, Thailand