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临床试验/NCT04694378
NCT04694378已完成不适用

Relationship Between Right Ventricular Free Wall Longitudinal Strain and Stroke Volume Index by Thermodilution in Patients Undergoing Cardiac Surgery

Tufts Medical Center1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2020年10月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
Change of right ventricular function during CABG assessed by right heart strain (%)

研究概览

简要总结

Patients undergoing coronary artery bypass grafting up tp 30% will develop postoperative right ventricle dysfunction. Its imperative for the physician to fully understand the severity of this complication in order to perform an early diagnosis and carry out the appropriate treatment.

Aim:

Investigate the correlation between echocardiographic measurements and hemodynamic changes at different time points in patients undergoing coronary artery bypass graft surgery

Hypothesis:

  1. Weak correlation between echocardiographic measurements and hemodynamic changes during coronary artery bypass graft surgery
  2. Echocardiographic measurements would change across different time points during surgery independent of hemodynamic values.

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Elective coronary artery bypass graft patients who require pulmonary catheter placement for intraoperative monitoring.

排除标准

  • Patients with contraindication to Swan-Ganz catheter placement,
  • Pre-existing atrial arrhythmias,
  • Patients with moderate and/or severe mitral/tricuspid valve stenosis or regurgitation
  • Patients with contraindication to transesophageal echocardiogram probe placement (i.e. esophageal stenosis).

结局指标

主要结局

Change of right ventricular function during CABG assessed by right heart strain (%)

时间窗: during CABG surgery

Assessing the change of RV function during CABG surgery using right heart strain as a percentage of change between RV shortening and RV end diastolic length.

Change of right ventricular function during CABG assessed by stroke volume index (mL/m2)

时间窗: during CABG surgery

Assessing the change of RV function during CABG surgery using stroke volume index. Stroke volume index measurement as millilitres per square meter (ml/m2)

次要结局

  • Change in cardiac output measured with Swan-Ganz during CABG(during CABG surgery)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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