Influence of Two Paraffin Wax Chewing Gums of Different Consistency on the Stimulated Saliva Flow Rate
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 81
- 试验地点
- 1
- 主要终点
- Stimulated salivary flow rate (ml)
研究概览
简要总结
The study examines two different chewing gums with regard to consistency and its influence on the result of sialometry
详细描述
The examination (sialometry) is performed on healthy volunteers. The volunteers must chew on a paraffin gum for seven minutes. After each minute, the amount of secreted saliva is spat into a designated cup and evaluated. This test is performed with Aurosan chewing gum and later with GC Europe chewing gum.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy volunteers
- •non-smoker
- •no medication
排除标准
- •physical or mental illnesses
- •regular medication intake
- •pregnant women
- •dementia or persons who are unable to judge or persons with guardianship
- •minor test persons
研究组 & 干预措施
stimulated salivary flow rate
stimulated salivary flow rate determined in a crossover design: first using Paraffin Pellets from Aurosan GmbH; thereafter using Chewing wax from the Saliva-Check Buffer from GC Europe
干预措施: Paraffin Pellets from Aurosan GmbH (Diagnostic Test)
stimulated salivary flow rate
stimulated salivary flow rate determined in a crossover design: first using Paraffin Pellets from Aurosan GmbH; thereafter using Chewing wax from the Saliva-Check Buffer from GC Europe
干预措施: Chewing wax from the Saliva-Check Buffer from GC Europe (Diagnostic Test)
结局指标
主要结局
Stimulated salivary flow rate (ml)
时间窗: at baseline (approx 40 minutes)
Comparing measurements of stimulated salivary flow rate (ml) after chewing two different chewing gums
次要结局
- Change in consistency of chewing gum(at baseline (7 minutes for each chewing gum))