NCT02026193已完成不适用
IVF Hyper-responders: Oocyte Vitrification Compared With Embryo Freezing
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- Fetal Heart Activity 1 Month Post Embryo Transfer
研究概览
简要总结
The chances to achieve pregnancy after retrieving >15 oocytes are not good, probably because of bad effect on the endometrium (uterine inner lining). Therefore, in most such cases the investigators prefer to freeze all embryos, and transfer in a thaw cycle. With the introduction of oocyte vitrification (very fast cooling) technology, a new option emerged: to freeze un-fertilized eggs, to be fertilized and used later in a thaw cycle.
The purpose of this study is to compare the outcome of these two approaches.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 40 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •IVF patients
- •ovulation trigger with Decapeptyl 0.2 mg because of ovarian hyper-response: E2 on trigger day .12,000 pmol/l and/or >15 oocytes.
- •Normal uterus
排除标准
- •<20% fertilization rate
结局指标
主要结局
Fetal Heart Activity 1 Month Post Embryo Transfer
时间窗: 1 month after embryo transfer
Fetal heart activity as demonsrated by vaginal ultrasound 1 month post embryo transfer
次要结局
未报告次要终点
研究者
Shahar Kol MD
Director, IVF Unit
Rambam Health Care Campus
研究点 (2)
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