NCT06325787已完成不适用
Long-term Comparison of Image-guided Thermal Ablation vs. Lobectomy for Solitary Papillary Thyroid Microcarcinoma: A Multicenter Retrospective Study
Chinese PLA General Hospital0 个研究点目标入组 1,021 人开始时间: 2013年5月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,021
- 主要终点
- disease-free survival
研究概览
简要总结
To evaluate the clinical outcomes of image-guided thermal ablation versus thyroid lobectomy for the treatment of papillary thyroid microcarcinoma
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •solitary papillary thyroid carcinoma confirmed by fine-needle aspiration or core-needle biopsy;
- •largest diameter ≤10 mm;
- •no evidence of extrathyroidal extension( no signs of unsmooth thyroid capsule or involvement of the perithyroidal tissue) on ultrasound;
- •no evidence of cervical lymph node metastasis on US or neck CT;
- •no distant metastasis on chest CT;
- •no history of neck irradiation.
排除标准
- •(1)aggressive subtype of papillary thyroid microcarcinoma confirmed by biopsy(1); (2)multiple tumors; (3) incomplete data or lost follow-up
结局指标
主要结局
disease-free survival
时间窗: more than 5 years
disease-free survival calculated from treatment initiation to disease progression or the last follow-up date
disease progression
时间窗: more than 5 years
cervical lymph node metastases, recurrent tumors and persistent tumors
次要结局
- complications(1 week)
- cost(1 week)
- hospitalization(1 week)
- procedure time(1 hour after treatment)
- estimated blood loss(1 hour)
研究者
Yu-kun Luo
Director, Head of Department of Ultrasound
Chinese PLA General Hospital
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