NCT04551287已完成不适用
Artificial Intelligence Enables Precision Diagnosis of Cervical Cytology Grades and Cervical Cancer
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University3 个研究点 分布在 1 个国家目标入组 16,164 人开始时间: 2019年7月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 16,164
- 试验地点
- 3
- 主要终点
- Area under ROC curve (AUC)
研究概览
简要总结
Cervical cancer, the fourth most common cancer globally and the fourth leading cause of cancer-related deaths, can be effectively prevented through early screening. Detecting precancerous cervical lesions and halting their progression in a timely manner is crucial. However, accurate screening platforms for early detection of cervical cancer are needed. Therefore, it is urgent to develop an Artificial Intelligence Cervical Cancer Screening (AICS) system for diagnosing cervical cytology grades and cancer.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 25 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women Aged 25-65 years old.
- •Availability of confirmed diagnostic results of the cervical liquid-based cytological examination, and satisfactory digital images from the liquid-based cytology pap test: at least 5000 uncovered and observable squamous epithelial cells, samples with abnormal cells (atypical squamous cells or atypical glandular cells and above).
排除标准
- •Unsatisfactory samples of cervical liquid-based cytological examination: less than 5000 uncovered, observable squamous epithelial cells, and more than 75% of squamous epithelial cells affected because of blood, inflammatory cells, epithelial cells over-overlapping, poor fixation, excessive drying, or contamination of unknown components.
- •Women diagnosed with other malignant tumors other than cervical cancer.
结局指标
主要结局
Area under ROC curve (AUC)
时间窗: Diagnostic evaluation will be performed within 1 week when the smear pictures are obtained
Area under the curve
次要结局
- Specificity(Diagnostic evaluation will be performed within 1 week when the smear pictures are obtained)
- Accuracy(Diagnostic evaluation will be performed within 1 week when the smear pictures are obtained)
- Sensitivity(Diagnostic evaluation will be performed within 1 week when the smear pictures are obtained)
研究者
Herui Yao
Principal Investigator
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
研究点 (3)
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