Glaucoma Respsosne to Lifestyle Corrections in Sleep Apnea
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Intraocular pressure
研究概览
简要总结
glaucoma is prevalent among obstructive sleep apnea (OSA). contnous passive airway pressure is main treatment of OSA. lifestyle corrections also recommended
详细描述
forty glaucoma patients (high tension priamry open angle form) with OSA, intraocular pressure more than 21 mmHg, and obesity will be involved and divided to group I or group II (number of patients will be twenty in every group) for three month. both groups will apply CPAP during night sleeping daily for three month. group I will apply lifestyle corrections (low calories diet intake and 3-session per-week 40-minute treadmill walking for three month.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 30 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Obstructive sleep apnea patients
- •obese patients
- •glaucoma (open angle form with ocular hyoertension)
排除标准
- •cardiac patients renal patients hepatic patients
研究组 & 干预措施
group number 1
twenty glaucoma patients (high tension priamry open angle form) with OSA, intraocular pressure more than 21 mmHg, and obesity will be involved in group I will apply CPAP during night sleeping daily for three month. group I will apply lifestyle corrections (low calories diet intake and 3-session per-week 40-minute treadmill walking for three month.
干预措施: lifetyle corrections and CPAP (Behavioral)
group number 2
twenty glaucoma patients (high tension priamry open angle form) with OSA, intraocular pressure more than 21 mmHg, and obesity will be involved in group II will apply CPAP during night sleeping daily for three month.
干预措施: CPAP (Other)
结局指标
主要结局
Intraocular pressure
时间窗: it will be measured after 12 weeks
it will be measured by tonometery
次要结局
- neck circumferfence(It will be measured after 12 weeks)
- apnea hypopnea index(It will be measured after 12 weeks)
- Epowrth sleepiness scale(It will be measured after 12 weeks)
- body mass index(It will be measured after 12 weeks)
- waist circumference(it will be measured after 12 weeks)
- glaucoma related quality of life questioanire(It will be measured after 12 weeks)
研究者
Ali Mohamed Ali ismail
lecturer of physical therapy for Cardiovascular, Respiratory disorder and Geriatrics, Faculty of Physical Therapy, Cairo University
Cairo University