跳至主要内容
临床试验/NCT04360538
NCT04360538进行中(未招募)不适用

Long Term Outcomes of Patients With COVID-19

University of Chicago2 个研究点 分布在 1 个国家目标入组 500 人开始时间: 2020年4月8日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
进行中(未招募)
入组人数
500
试验地点
2
主要终点
Quality of Life score

研究概览

简要总结

The investigators hypothesize that those with respiratory failure due to COVID-19 will have different burdens of mental and physical disability than those with respiratory failure who do not have COVID-19. Detecting these potential differences will lay an important foundation for treating long term sequelae of respiratory failure in these two cohorts.

详细描述

The aim of this proposal to is to understand the extent and degree of physical disability, psychological sequelae, and cognitive dysfunction survivors of COVID-19 related critical illness will have upon hospital discharge, 6 months, and up to one year post discharge. These outcomes of interest will be evaluated prospectively. The investigators will perform these measures in Covid-19 patients with respiratory failure and compare them to non-Covid-19 patients with respiratory failure. The investigators also seek to determine the risk factors of these long-term complications in order to guide providers as to which patients should be screened for these deficits. Finally, the investigators will examine the association of various critical care interventions such as invasive versus noninvasive mechanical ventilation or use of sedatives and their effects on disability and cognitive dysfunction.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • adult patients admitted to the ICU

排除标准

  • 未提供

研究组 & 干预措施

COVID19 positive

ICU patients coronavirus positive

干预措施: Quality of Life (Other)

COVID19 positive

ICU patients coronavirus positive

干预措施: Impact Event Score (Other)

COVID19 positive

ICU patients coronavirus positive

干预措施: Hospital anxiety and depression scale (Other)

non-COVID19

ICU patients without coronavirus

干预措施: Quality of Life (Other)

结局指标

主要结局

Quality of Life score

时间窗: up to 12 months after discharge

SF-36 score

次要结局

  • Psychological Sequelae(up to 12 months after discharge)
  • cognitive dysfunction(up to 12 months after discharge)
  • Functional Status Score(up to 12 months after discharge)
  • Physical Disability(up to 12 months after discharge)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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