Eating Disorders Genetics Initiative 2
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20,000
- 试验地点
- 5
- 主要终点
- Number of Participants Identified with an Eating Disorder Diagnosis by Category
研究概览
简要总结
The overarching intention of the Eating Disorder Genetics Initiative 2 (EDGI2) is to increase sample size, diversity, and eating disorder phenotypes. The investigators are enrolling 20,000 new participants with anorexia nervosa (AN), bulimia nervosa (BN), binge-eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and controls in the US, Mexico, Australia, New Zealand, Sweden, and Denmark. A primary study goal is to enroll at least 30% of participants from underrepresented groups. Participants are asked to complete a series of questionnaires and submit a saliva sample for genotyping. The goal is to better understand eating disorders and how they relate to each other so that better treatments can be developed.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Other
入排标准
- 年龄范围
- 12 Years 至 99 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •A lifetime history of anorexia nervosa, bulimia nervosa, binge-eating disorder, avoidant restrictive food intake disorders or no history of any disordered eating behavior, based on DSM-5 criteria algorithms
- •Age 12-99 years, depending on country. (US enrollment age is 18-99)
排除标准
- •History of subthreshold disordered eating behaviors.
结局指标
主要结局
Number of Participants Identified with an Eating Disorder Diagnosis by Category
时间窗: Baseline
The ED100Kv4 is a web-based diagnostic questionnaire, based on the Structured Clinical Interview for Axis 1 Disorders, that applies algorithms to participant responses. The number of participants with each diagnosis (AN, BN, BED, ARFID, and control) will be reported.
Age of eating disorder onset
时间窗: Baseline
Age of eating disorder onset will be considered as the age of first eating disorder symptom as self-reported in the ED100Kv4 questionnaire (ED100K). Age of onset will be reported for each eating disorder group.
次要结局
- Current Disordered Eating Symptoms(Baseline)
- Mental Health and Behavior(Baseline)
- Mood - Lifetime history of mood and anxiety disorders(Baseline)
- Self-Violence(Baseline)
- Lifetime Substance Use(Baseline)
- Life-Events(Baseline)
- Eating Disorder Quality of Life(Baseline)
- Compulsive Exercise Test(Baseline)
- Perfectionism(Baseline)