ISRCTN10257246进行中（未招募）Unknown
First-in-man evaluation of a fibre optic sensor to monitor ventilatory oscillations in the arterial partial pressure of oxygen in real-time: a feasibility study in patients with the acute respiratory distress syndrome
适应症
试验速览
- 阶段
- Unknown
- 状态
- 进行中（未招募）
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 性别
- All
入选标准
- •1. Adult patient =18 years
- •2. Mechanically ventilated and sedated in controlled ventilation
- •3. PaO2 to inspired oxygen fraction (FiO2) ratio (P/F) =26.6 kPa
- •4. Indwelling arterial catheter
- •5. Planned for a PEEP change from 15 to 5 cmH2O to measure the recruitment to inflation ratio (R/I ratio)
排除标准
- •1. Pregnancy
- •2. Respiratory failure due to acute heart failure
- •3. Severe hemodynamic instability defined as either continuous infusion of noradrenaline (NA) at a rate >0.5 micrograms/kg/minute, or the presence of at least one cardiac support device: intra-aortic balloon pump (IABP), Impella, Veno-arterial extra-corporeal membrane oxygenation (VA-ECMO)
- •4. Tidal volume (Vt) <3 ml/kg of body weight
- •5. Respiratory rate (RR) >30 breaths/minute
- •6. Peripheral oxygen saturation (SpO2) <90%
研究者
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