Pre and Post-arterial Recanalization Imaging of Central Retinal Artery Occlusions (CRAO)
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 63
- 试验地点
- 1
- 主要终点
- Contrast enhancement of the ophthalmic artery
研究概览
简要总结
Central retinal artery occlusions (CRAO) are the equivalent of an ischemic stroke at the retinal level. They share the same risk factors and common pathology. The diagnosis of a CRAO is clinically based on the sudden occurrence of a decrease in deep visual acuity with fundamentally signs of reactive ischemia.
Small studies have highlighted the value of cerebral MRI (Magnetic Resonance Imaging) in CRAO with almost 25% of ischemic strokes found on diffusion sequences and the demonstration of a correlation between anomalies in diffusion sequence and the probability of a pathology with a high risk of recurrence (carotid stenosis or emboligenic cardiopathy). But there are usually few radiological signs that allow a direct positive diagnosis of CRAO, an etiologic diagnosis or a prognosis. This descriptive study will focus on CRAO at the diagnostic and post-treatment phases in the short and medium term, in order to (i) identify imaging etiologic signs of CRAO with specific sequences from a 3 Tesla MRI, (ii) identify positive diagnostic signs of CRAO with the same specific sequences, (iii) correlate these signs with the visual prognosis one month after the CRAO.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •18 years of age or older
- •CRAO (onset of symptoms ≤ 48 hours)
- •Consent to participate in the study
排除标准
- •- Contraindications to 3 Tesla MRI
结局指标
主要结局
Contrast enhancement of the ophthalmic artery
时间窗: Baseline
Binary variable (yes/no)
Presence of a thrombus
时间窗: Baseline
Binary variable (yes/no)
Restriction of the apparent diffusion coefficient (ADC) at the optic nerve level and at the papilla level
时间窗: Baseline
Binary variable (yes/no)
Hypersignal of the ophthalmic artery in diffusion
时间窗: Baseline
Binary variable (yes/no)
Presence of an arterial stenosis of the supra aortic trunks
时间窗: Baseline
Binary variable (yes/no)
次要结局
未报告次要终点
