EUCTR2006-003075-12-IE进行中（未招募）1 期
Effect of carvedilol on left ventricular systolic and diastolic function and the neurohormonal axis in patients with Duchenne muscular dystrophy and left ventricular dysfunction.
Department Of Paediatric Cardiology0 个研究点目标入组 30 人开始时间: 2006年7月13日最近更新:
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •1.Diagnosis of confirmed DMD with either dilated LV (>2Z scores) and depressed LV systolic function (LVEF <40%).
- •2.Agreement to participate.
- •3.Patients already treated with afterload reduction (ACE inhibitors), digitalis or diuretics will not be excluded as they will act as their own controls in determining positive or negative effects of carvedilol.
- •Are the trial subjects under 18? yes
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) no
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •1.Refusal to participate.
- •2.Severe asthma which would be exacerbated by beta-blockade
- •3.Glucose intolerance or diabetes mellitus.
- •4.Severe claustrophobia which would prevent MR.
- •5.Any major contra-indication to cardiac MRI
研究者
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