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临床试验/NCT04188496
NCT04188496已完成不适用

The Effects of Thoracic Joint Mobilization on Pulmonary Functions of Patients With Stroke

Shehla Gul2 个研究点 分布在 1 个国家目标入组 26 人开始时间: 2016年2月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
Shehla Gul
入组人数
26
试验地点
2
主要终点
Forced expiratory Volume in one sec (FEV1)

研究概览

简要总结

Stroke a neurological disorder leads to long term disability and decline in overall quality of life. Pulmonary Functions are usually impaired in individuals with stroke. The common findings associated with pulmonary functions in Stroke patients are Decreased lung volumes, decreased pulmonary perfusion and vital capacity and altered chest wall excursion. For stroke patients, general rehabilitation programs, only aims towards their functional recovery of the body. The main focus of this study was to integrate intervention and implement them in rehabilitation programs that are related to respiration are more effective for improving functional activities.in stroke patients. The study was carried out to determine the effects of thoracic Joint Mobilization on Pulmonary Functions of patients with stroke.

详细描述

INTRODUCTION Stroke is defined as sudden neurological deficit due to an abnormality in cerebral blood flow, with sign and symptoms lasting for more than 24 hours. Strokes can be grouped into two fundamental classification according to the American Stroke Association (ASA), first is ischemic (87%) and the second is Hemorrhagic (13%). In epidemiological and genetic studies a stroke subtype classification is useful indicator in our clinical practice. Many serious physical and cognitive deficits results due to injury to the brain tissue. Depending upon the region of the brain that is involved and amount of damage, a person can recovers from stroke.

Stroke is associated with many primary and secondary complications. Here mentioned some primary complications. Sensation, Pain, Visual changes, Motor Function, Weakness, Alternation in Tone, Abnormal Reflexes, Altered Coordination, Altered Postural control and Balance. The main Indirect or secondary complications are Musculoskeletal Complications, Neurological Complications, Cardiovascular Complications, Pulmonary Complications, and Integumentary Complications.

Pulmonary Functions are usually impaired in individuals with stroke. The common findings associated with pulmonary functions in Stroke patients are Decreased lung volumes, decreased pulmonary perfusion and vital capacity and altered chest wall excursion. Individuals with stroke are, associated with dysphagia which leads to dehydration and compromised nutrition. Dysphagia has been related with enlarged risk of pulmonary difficulties and also death. According to research evidence primary findings of dysphagia in patients having acute stroke significantly decreases complications. It also decreases the length of hospital stay and overall health expenditure.

Dysphagia further leads to Aspiration. Aspiration, is penetration of food, liquid, saliva or gastric reflux into the airways. It usually occurs in acute phase of recovery or during swallowing. Aspiration is an important complication and can leads to aspiration pneumonia if left untreated, death can occur.

Impaired Pulmonary functions limits physical activities as well. Because the decreased respiratory output is accompanied by increased oxygen demands required during altered movement patterns in stroke. Furthermore people with stroke usually undergo irregular breathing because of damage to the respiratory muscles (such as Diaphragm).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
30 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • A sample of 26 patients with stroke without any history of recent pulmonary involvement
  • Diagnosed with stroke by computed tomography (CT) or magnetic resonance imaging (MRI), with disease duration of at least six months after the onset of stoke.
  • Score 24 points or higher on MMSE to ensure that they able to understand and follows the researcher's order.

排除标准

  • The subjects having any recent surgery,
  • unstable blood pressure and
  • having acute infections were excluded from the study.

结局指标

主要结局

Forced expiratory Volume in one sec (FEV1)

时间窗: 6 months

Pulmonary Functions: Forced expiratory Volume in one sec (FEV1) was measured in litre/sec through digital spirometer

Forced vital capacity (FVC)

时间窗: 6 months

Pulmonary Functions: Forced vital capacity (FVC) was measured in litre through digital spirometer

次要结局

未报告次要终点

研究者

发起方
Shehla Gul
申办方类型
Indiv
责任方
Sponsor Investigator
主要研究者

Shehla Gul

Principal Investigator

Gul, Shehla

研究点 (2)

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