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临床试验/NCT03298737
NCT03298737Enrolling By Invitation不适用

Visual Attention and Eye Movements

University of Rochester1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2017年10月26日最近更新:
适应症

试验速览

阶段
不适用
状态
Enrolling By Invitation
入组人数
20
试验地点
1
主要终点
Pursuit eye movements to peripheral moving stimuli

研究概览

简要总结

The purpose of this study is to provide information about how the brain processes sensory inputs using visual stimuli throughout various psychophysical experiments.

详细描述

This laboratory studies visual perception with a focus on the interaction between eye movements and attention. It is well established that attending to a stimulus can profoundly alter perception. For example, attending to a speaker at a crowded party can almost completely filter background both in terms of auditory noise and visual distractions. Although laboratory studies have traditionally investigated the effects of attentional changes in the absence of eye movements, under natural conditions, visual attention is often accompanied by orienting movements to direct our head and eyes towards the relevant objects of interest. Recent work has suggested that these orienting movements affect perception in a manner similar to covert attention. The proposed studies will investigate how eye movements contribute to perception and attention.

The research covered by this protocol combines traditional "button-press" psychophysics with non-invasive eye-tracking to investigate the interaction between eye movements and perception. Subjects will perform simple perceptual tasks, such as judging the orientation or direction of a visual stimulus, while their eye position is monitored with a video eye-tracker. This approach (combining psychophysics and eye-tracking) is flexible, low risk, and fast when compared with neurophysiological studies. However, by focusing on low-level perceptual tasks, the results will be interpretable in the context of larger studies of neurophysiological responses in the visual system.

The investigators hope that this basic research will ultimately have both applied and clinical significance. For example, understanding how perception is influenced by attention and eye-movements in neurotypical populations may provide non-invasive and naturalistic ways to identify and diagnose psychiatric disorders. Additionally, understanding how eye-movements interact with sensory encoding has the potential to improve machine learning algorithms for vision and navigation (These are not a part of the current study, but a potential future impact).

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age between 18-65
  • Corrected-to-normal vision
  • No known diagnosis of visual or auditory disorder or impairment

排除标准

  • Does not have corrected-to-normal vision
  • Unable to understand and follow the instructions given of the study
  • Known diagnosis of visual or auditory disorder or impairment

结局指标

主要结局

Pursuit eye movements to peripheral moving stimuli

时间窗: baseline

Pursuit eye movements are smooth eye movements with slow velocities (\< 15 degs/sec) that track the motion of visual stimuli when they are at the center of the visual field (Madelain and Krauzlis, J. of Vision, 2003). Here we will test the prediction that pursuit eye movements begin to track the motion of the stimulus located peripherally as an eye movement moves to the stimulus. The null hypothesis is that there will be no effect of the peripheral stimulus motion on the pursuit eye movements. We will measure eye movements using an infra-red eye tracker (Arrington, Inc) from 500 or more trials collected in each session. The distribution of pursuit eye movements will be computed for each subject to evaluate if there is significant pursuit along the direction of stimulus motion around the time of the saccade. The mean per participant will be determined and group effects evaluated.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jude Mitchell

Assistant Professor

University of Rochester

研究点 (1)

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