Pragmatic, multicentre, randomised controlled trial evaluating a routine molecular Point-of-Care ‘test-and-treat’ strategy for influenza in adults hospitalised with acute respiratory illness: FluPOC

niversity Hospital Southampton NHS Foundation Trust0 个研究点目标入组 613 人开始时间: 2017年11月13日最近更新: 2021年6月7日

适应症

试验速览

•1. Is a patient in the ED* or AMU at University Hospital Southampton NHS Foundation Trust (UHS) or [added 01/05/2019]: Hampshire Hospitals Foundation NHS Trust
•2. Aged =18 years old
•3. Has acute respiratory illness**
•4. Duration of respiratory illness less than 10 days prior to hospitalisation
•5. Can be recruited to the study within 16 hours of presentation
•*For patients in ED a decision will have already been made that the patient will be admitted.
•**An episode of acute respiratory illness is defined as an acute pulmonary illness (including pneumonia, bronchitis and influenza-like illness) or an acute exacerbation of a chronic respiratory illness (including exacerbation of COPD, asthma or bronchiectasis). For the study, acute respiratory illness as a provisional, working, differential or confirmed diagnosis must be made by a treating clinician.

•1. Not fulfilling all the inclusion criteria
•2. A purely palliative approach being taken by the treating clinicians
•3. Previously included in this study and re-presenting within the last 30 days after hospital discharge
•4. Declines nasal / pharyngeal swabbing
•5. Consent declined or consultee consent declined
•6. Concurrent, prior or subsequent enrolment in an observational study is not necessarily an exclusion criterion; this is at the discretion of the chief investigator and will be assessed on a case-by-case basis.

发起方

niversity Hospital Southampton NHS Foundation Trust