ISRCTN23758980已完成未知
REducing and preventing COgnitive impairment iN older age groups (the RECON Programme) feasibility trial
niversity of Southampton0 个研究点目标入组 20,000 人开始时间: 2018年8月1日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 20,000
研究概览
简要总结
2020 Protocol article in https://pubmed.ncbi.nlm.nih.gov/33216010/ protocol (added 23/11/2020) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/36203694/ (added 06/09/2023)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •Participant inclusion criteria as of 11/10/2018:
- •Cognitively impaired participants:
- •1. Aged between 60 and 85 years old
- •2. Have cognitive impairment: 1 SD below the norm for the Baddeley reasoning test. We will explore the impact in subgroups defined by combinations of impairment in Baddeley reasoning, IADL and memory. Key subgroups for those with cognitive impairment that are of particular interest are:
- •2.1. AACD: 1SD below norm for an average of 3 tests for Baddeley reasoning + 1sd below norm for Instrumental activities of Daily Living (IADL)
- •2.2. MCI: 1.5SD below norm for an average of 3 tests for Baddeley reasoning + 1.5 SD below norm for an average of 3 tests for impaired memory (self-ordered search test)
- •3. Be willing and able to access the internet
- •Non-Cognitively impaired participants:
- •To be eligible for inclusion individuals without signs of cognitive decline will:
- •1. Be aged between 60 and 85 years old
- •2. Have normal cognitive function (i.e. do not meet criteria for inclusion in the cognitively impaired trial)
- •3. Be willing and able to access the internet
- •Previous participant inclusion criteria:
- •To be eligible for inclusion, individuals with signs of cognitive decline will:
- •1. Be aged between 60 and 85 years old
- •2. Have either MCI (defined as 1.5 SD below the norm in a non-memory cognitive domain plus memory impairment or AACD (defined as 1 SD below the norm for the Baddeley reasoning test)
- •3. Be willing and able to access the internet
- •To be eligible for inclusion individuals without signs of cognitive decline will:
- •1. Be aged between 60 and 85 years old
- •2. Have normal cognitive function (i.e. do not meet criteria for MCI or AACD)
- •3. Be willing and able to access the internet
排除标准
- •1. Have an existing diagnosis of dementia
- •2. Report high levels of leisure time physical activity already (i.e. score 30 or more on the Godin Leisure Time Exercise Questionnaire (counting moderate or vigorous physical activity only))
- •3. Do not have access to the internet
- •Individuals without signs of cognitive decline will be excluded if:
- •1. In full time employment (or are fully retired)
- •2. Have an existing diagnosis of dementia
- •3. Report high levels of leisure time physical activity already (i.e. score 30 or more on the Godin Leisure Time Exercise Questionnaire (counting moderate or vigorous physical activity only))
- •4. Do not have access to the internet
研究者
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