NCT03539575进行中（未招募）不适用
CB1R Availability in Synthetic Psychoactive Cannabinoid Users
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 15
- 试验地点
- 1
- 主要终点
- Positron Emission Tomography (PET Imaging)
研究概览
简要总结
The purpose of this research study is to determine whether the CB1R availability is lower in synthetic psychoactive cannabinoid subjects using the most widely available synthetic psychoactive cannabinoids at the time the study is initiated.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Other
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Able to provide written consent
- •Age 18-55
- •Current Synthetic Psychoactive Cannabinoids consumption
排除标准
- •MRI metal exclusions and claustrophobia
- •Education completed is less than 12 years
研究组 & 干预措施
Synthetic Psychoactive Cannabinoid Users
Other
Synthetic Psychoactive Cannabinoid dependent subjects who are frequent spice/K2 users will receive the radiotracer [11-C]OMAR.
干预措施: [11-C]OMAR (Other)
结局指标
主要结局
Positron Emission Tomography (PET Imaging)
时间窗: Change in CB1R availability from baseline throughout one test day
CB1R availability using \[11-C\]OMAR PET imaging Change in CB1R availability (e.g. volume distribution).
次要结局
- Electroencephalogram(Change in CB1R availability from baseline throughout one test day)
- CogState Battery(Change in CB1R availability from baseline throughout one test day)
研究者
Deepak C. D'Souza
Professor of Psychiatry
Yale University
研究点 (1)
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