IRCT20081207001494N3招募中3 期
Evaluation of the efficacy of N-Acetylcysteine and vitamin E supplementation on oxidative stress status in patients with transfusion-dependent ß-thalassemia
适应症
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 75
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 no limit（—）
- 性别
- All
入选标准
- •All patients with transfusion-dependent beta-thalassemia above 18 years old who were diagnosed by clinical history, and hemoglobin electrophoresis.
- •Receiving regular blood transfusion (15 cc/kg body weight with interval of 3-4 weeks to maintain hemoglobin levels above 9.5 g/dl)
- •Treating by at least one or combination of iron chelation therapy agents including deferasirox (DFX), deferiprone (DFP), and deferoxamine (DFO).
排除标准
- •No desire to participate in the study
- •Being positive for hepatitis B, C or HIV
- •Presentation of any acute infectious disease
- •Narcotic addiction
- •Under treatment with nitroglycerine or other related drugs
- •Known allergy to NAC
研究者
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