KCT0005565招募中未知
Effects of Bifidobacterium on Skin Wrinkle, Hydration, TEWL, Elasticity and Gloss: a randomized, double-blind, placebo controlled, and parallel clinical trial
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 入组人数
- 170
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 30(Year) 至 60(Year)（—）
- 性别
- Female
入选标准
- •? Korean female subjects who aged between 30 and 60 years.
- •? Participants who have dry skin on cheek (hydration value is below 48 A.U. by Corneometer®).
- •? Participants who have skin wrinkle over 3 grade by DERMAPRO standard photograph.
- •? Participants who don’t have any chronic or acute disease including skin disease.
- •? Participants who signed and informed consent of the study.
- •? Participants who are cooperative and available for follow-up during the study period.
排除标准
- •? Participant who have consumed probiotics as dietary supplements, food or beverage products during the last two weeks.
- •? Participants who are pregnant, nursing or planning to become pregnant.
- •? Participants who have irritation or symptomatic allergy for food including ingredients of cosmetic, medical and test product.
- •? Participants who take oral or topical antibiotics during the previous 3 months.
- •? Participants who take oral retinoid/steroid drug or topical application included steroid during previous 6 months.
- •? Participants who use functional cosmetics for improvement of skin wrinkle, hydration and elasticity within 3 months.
- •? Participants who have an experience on test site (skin decortications, botox and other skin treatment).
- •? Participants who participate in a previous study without an appropriate intervening period (three month) between studies.
- •? Participants who have disease which affected the study (e.g. cardiovascular, kidney, liver, thyroid, gastrointestinal disease, gout).
- •? Participants who have any skin disease (e.g. atopic dermatitis) in test site.
- •? Participants who have any chronic disease (e.g. diabetes, asthma, high blood-pressure) or psychiatric disorder (e.g. depression, schizophrenia, alcoholism, drug addiction).
- •? Participants who take a medicine for treatment of obesity (e.g. antidepressants, anorectics), contraceptives, hormones or diuretics
- •? Participants who take excessive alcohol (over 30g alcohol per day).
- •? Participants who has sensitive or hypersensitive skin.
- •? Participants who have damaged skin in or around the test area which includes sunburn, tattoos, scars or other disfiguration on the test area.
- •16 Participants who have an abnormal result in screening clinical chemical analysis by medical specialist
- •17 Participants who have a problem which may interfere with the aim of the study as the judgment of the principal investigator.
研究者
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