Determination of Optimal Positive End-expiratory Pressure Using Electrical Impedance Tomography in Children Under General Anesthesia: Comparison Between Supine and Prone Positions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 33
- 试验地点
- 1
- 主要终点
- Optimal PEEP level at spine position
研究概览
简要总结
The purpose of this study was to determine the appropriate positive end-expiratory pressure (PEEP) using electrical impedance tomography (EIT) in children under general anesthesia and to investigate whether there is a difference between the supine and prone positions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- — 至 1 Year（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children <= years of age who are scheduled for surgery in the prone position under general anesthesia
排除标准
- •Respiratory distress, bronchopulmonary dysplasia
- •Pneumothorax
- •Increased intracranial pressure
- •History of airway surgery
- •Cervical or thoracic surgery
- •Pulmonary hypertension
研究组 & 干预措施
Children <= 1 years old
Pediatric patients <= 1 years old of age scheduled for surgery in the prone position
干预措施: Exploration of optimal PEEP in supine and prone position (Other)
结局指标
主要结局
Optimal PEEP level at spine position
时间窗: 10 minutes after intubation (supine)
Optimal PEEP level (cmH2O) determination using electrical impedance tomography at supine position
Optimal PEEP level at prone position
时间窗: 1 hour after prone positioning (prone)
Optimal PEEP level (cmH2O) determination using electrical impedance tomography at prone position
次要结局
- pulmonary opening pressure measured using Electrical impedance tomography(until 1 hour after prone positioning)
- Dynamic compliance measured using Electrical impedance tomography(until 1 hour after prone positioning)
- regional ventilation delay measured using Electrical impedance tomography(until 1 hour after prone positioning)
- atelectasis/overdistension ratio measured using Electrical impedance tomography(until 1 hour after prone positioning)
研究者
Hee-Soo Kim
Professor
Seoul National University Hospital