NCT00867555已完成不适用
Effects of the Green Tea Extract TEAVIGO High in EGCG, on Postprandial Fat Oxidation in Overweight Volunteers
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- postprandial fat oxidation
研究概览
简要总结
The body of evidence regarding the health benefits of green tea has grown considerably during the last decade and includes antioxidant properties, anti- cancer, anti-obesity and anti-diabetes effects. There has been evidence that green tea extract favorably affect body weight and body fat and has positive effects on blood glucose control
Aim of this study is to investigate the short term effect (3-day)of TEAVIGO (high in the catechin EGCG) on postprandial fat oxidation during different phases of the postprandial period in overweight subjects. Secondly, in a subset of volunteers changes in lipolysis and glucose metabolism will be studied in skeletal muscle and adipose tissue.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 20 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Age between 20 and 50 y
- •BMI 25.0-29.9 kg/m2
- •Normal fasting glucose <6.1 mmol/L
- •Blood pressure (systolic blood pressure 100-150 mmHg, diastolic blood pressure 60-90 mmHg)
- •Weight stable in last 3 months (±2 kg)
排除标准
- •pregnant, lactating or (post)menopausal women
- •regular smokers
- •people with intensive fitness training eg athletes
- •habitual consumption of green or black tea (more than 1 or 2 cups a day, respectively)
- •not more than 300 mg/day caffeine consumption
结局指标
主要结局
postprandial fat oxidation
时间窗: 8 months
次要结局
未报告次要终点
研究者
研究点 (2)
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