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临床试验/IRCT201107233449N8
IRCT201107233449N8已完成未知

Evaluating N-acetylcysteine efficacy in the prevention of amphotericin B-induced nephrotoxicity

Tehran University of Medical Sciences0 个研究点目标入组 60 人开始时间: 待定最近更新:
适应症

试验速览

阶段
未知
状态
已完成
入组人数
60

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

年龄范围
18 years 至 65 years(—)
性别
All

入选标准

  • 1- Age between 18 to 65 years
  • 2- Hemodynamica stability (Mean arterial pressure > 70 mmHg and Systolic blood pressure > 90 mmHg)
  • 3- Receiving AmB for treatment of fungal infections
  • Exclusion criteria
  • 1- Documented history of acute kidney injury or chronic kidney disease
  • 2- The status of kidney function at baseline is unknown
  • 3- Receiving N-acetylcysteine (oral or parenteral) recently (during the last 1 month)
  • 4- Documented history of hypersensitivity/anaphylactic reactions to N-acetylcysteine
  • 5- Co-administration of antioxidants (e.g. vitamin E, vitamin C)

排除标准

  • 未提供

研究者

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