NCT01791400已完成2 期
Study of Effects of Metoclopramide Versus Sumatriptan on Migraine Headache
适应症
干预措施
相关药物
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 124
- 试验地点
- 1
- 主要终点
- pain
研究概览
简要总结
The purpose of this study is to determine which drug makes lower migraine headache
详细描述
There are different options to manage benign headache in emergency department.The investigators compared Intravenous metoclopramide with Subcutaneous sumatriptan to relieve pain in emergency department.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 20 Years 至 60 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •20-60 years old and presented with acute headache similar to previous episodes,
- •with or without phonophobia,
- •photophobia,
- •vomiting or nausea.
排除标准
- •fever or neck stiffness,
- •altered mental state,
- •pregnancy,
- •recent trauma or seizure (within 24 hours),
- •focal neurological abnormality on physical examination,
- •allergy to metoclopramide,
- •hypertension,
- •cardiovascular diseases.
- •Also if the patients had taken a triptan or ergot during the last 24 hours were excluded from the study.
研究组 & 干预措施
Metoclopramide
Other
Patients who underwent 20 mg Metoclopramide intravenous one time
干预措施: metoclopramide, injection,20mg, one time (Drug)
sumatriptan
Other
Patients who underwent 6 mg sumatriptan subcutaneous one time
干预措施: Sumatriptan, injection, 6 mg, one time (Drug)
结局指标
主要结局
pain
时间窗: at one hour after prescription
determining pain in Metoclopramide versus sumatriptan groups
次要结局
未报告次要终点
研究者
Hamidreza Shemshaki
Research Assistant
Isfahan University of Medical Sciences
研究点 (1)
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