NCT03487861Unknown不适用
Development of a Diagnostic Kit for Urinary Transglutaminase 2 as a Biomarker for Kidney Allograft Fibrosis
适应症
试验速览
- 阶段
- 不适用
- 入组人数
- 1,000
- 试验地点
- 1
- 主要终点
- change of level of urinary transglutaminase 2
研究概览
简要总结
The aim of this study is to verify the ability of transglutaminase type 2 to predict rejection or chronic allograft nephropathy of renal allograft. On the basis of biomolecular mechanisms aggravating chronic allograft nephropathy, we eventually expect to develop the remedy to prevent chronic allograft nephropathy after kidney transplantation.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •kidney transplant recipients from cadaveric or living donors
- •kidney transplant recipients who take immunosuppressants regularly
- •kidney transplant recipients who voluntarily agree to participate in this trial
排除标准
- •multiorgan transplant recipients
- •kidney transplant recipients with active infection
- •kidney transplant recipients with alcohol or drug addiction
结局指标
主要结局
change of level of urinary transglutaminase 2
时间窗: 3 days, 7 days, 1 month, 3 months, 6 months post-transplant
次要结局
未报告次要终点
研究者
Sung Shin
Associate professor
Asan Medical Center
研究点 (1)
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