End-of-Life Decisions in Surgical Intensive Care Medicine - The Relevance of Treatment Withholding
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 226
- 主要终点
- sequence of withdrawing life-sustaining treatment
研究概览
简要总结
The purpose of this retrospective observational study is to describe the sequence of ICU-therapies that are limited and to compare characteristics and the decision making process in surgical ICU-patients.
详细描述
Decisions to limit life-support therapy are common on the intensive care unit (ICU). End-of-life decisions (EOLD) underlie a dynamic process and limitation of ICU-therapies is done sequentially. Questionnaire-based and observational studies on medical ICUs and in palliative care reveal blood transfusions as the first therapy physicians withhold in EOLDs. Whether this practice also applies to surgical ICU-patients is unknown.
The purpose of this retrospective observational study is to describe the sequence of ICU-therapies that are limited and to compare characteristics and the decision making process in surgical ICU-patients.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All surgical patients admitted to the ICU All surgical patients discharged death from the ICU
排除标准
- •All patients discharged alive from the ICU
结局指标
主要结局
sequence of withdrawing life-sustaining treatment
时间窗: 3 years
The primary objective of this study performed according to an observational post-ad-hoc design is to identify the sequence of withdrawing life-sustaining treatment in surgical ICU-patients with an end-of-life decision on an intensive care unit of a German academic medical center. Approximately 200 patients will be enrolled in the study. They are followed up until their death on the ICU. In clinical routine end-of-life decisions are documented for decision-makers and procedures in the patients´ records. Patients´ characteristics and therapeutic approaches are documented in the electronic patient data management system.
次要结局
- factors associated with the withholding of specific ICU-therapies(3 years)
研究者
Jan Adriaan Graw
Dr. med.
Charite University, Berlin, Germany