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临床试验/CTRI/2023/09/057956
CTRI/2023/09/057956尚未招募3 期

A Comparative Clinical Study of Varatika Bhasma and Abha Guggulu in the Management oF Osteoporosis

Dr Jaykishan1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年5月10日最近更新:

试验速览

阶段
3 期
状态
尚未招募
发起方
入组人数
40
试验地点
1
主要终点
increase in Bone Mineral Density

研究概览

简要总结

Osteoporosis is defined as a reduction in the strength of bone that leads to an increased risk of fractures. Loss of bone tissue is associated with deterioration in skeletal micro-architecture. condition is particularly common in elderly people and more frequent in postmenopausal women. World Health Organization defines osteoporosis as “A disease characterized by low bone mass and micro-architectural deterioration of bone tissue, leading to enhanced bone fragility and a consequent increase in fracture risk.In osteoporosis, there is a long latent period before clinical symptoms develop. The most prevalent complications are fractures of vertebral bodies, ribs, proximal femur, humerus, and distal radius with minimal trauma. Varatika Bhasma is mentioned in Bhaishjya Ratnavali in Bhagna Roga Adhikara.Varatika Bhasma (Cypraea moneta Linn) is Katu Rasa, Rooksha-Tikshna Guna, Ushna Virya, KatuVipaka, and Vatahara.   A**bha Guggulu is mentioned in Bhaishjya Ratnavali in Bhagna Adhikara.Ingredients of Abha Guggulu- Babul, Haritaki, Vibhitaki, Amalaki, Maricha, Pippali, Sunthi, Guggulu, Ghrita**Abha Guggulu is the predominance of Katu rasa, Laghu-Ruksha-Tikshna Guna, Ushana virya, Madhura Vipaka, and Karma are Vatahara, Rasayana, Vayahsthapana.

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Open Label

入排标准

年龄范围
40.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • 1.Patients were selected between the age group of 40-70 years 2.Patients of Osteoporosis diagnosed by B.M.D test (t-score < -2.5) 3.Patients having clinical features of osteoporosis.
  • Extreme fatigue, Body pain, Pain in back, Pain in vertebra, Hip, distal forearm, tibia, Hair loss, Dorsal kyphosis, Fracture after minimal trauma.

排除标准

  • 1.Patients below the age of 40 years and above the age of 70 years 2.Patients suffering from pathological Osteoporosis and neoplasms of the bone like osteoma and osteosarcoma 3.Hypercalcemia.

结局指标

主要结局

increase in Bone Mineral Density

时间窗: On day 91

次要结局

未报告次要终点

研究者

发起方
Dr Jaykishan
申办方类型
Other [self]

研究点 (1)

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