RBR-2vrm3f招募中未知
Evaluation of the efficacy of Behavioral Psychotherapy compared to pharmacotherapy in the treatment of Depressive Disorder in Temporal Lobe Epilepsy with Hippocampal Sclerosis
Instituto de Psiquiatria do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo0 个研究点开始时间: 2020年7月20日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 招募中
- 发起方
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Intervention
入排标准
- 年龄范围
- 18Y 至 59Y（—）
入选标准
- •Must have a TLE-HS; must be age 18 to 59 years old; must meet the DSM-5 criteria for major depression; must be willing to provide written informed consent; must be compliant, cooperative, reliable, and able to follow instructions, and to visit the clinic on schedule; must have an intellectual level (IQ) of 80 or more; must have a diagnosis of active epilepsy for at least six months and be receiving appropriate neurological treatment; doses of the antiseizure medication should be stable at least eight weeks ago, to start to receive a treatment of this study.
排除标准
- •Have other epileptic syndromes; presence of injury detectable to brain MRI other than that characterizing HS; history of other central nervous system disorder, such as meningitis, tumor, multiple sclerosis or traumatic brain injury; have clinical signs of drug intoxication or any other condition that may cause or predispose to severe impairment of cognition; have diagnosis of psychotic disorder, even though this condition is under remission; have severe psychiatric disorder requiring emergency treatment (e.g. psychosis); have active suicidal or homicidal ideation; have current alcohol or other substance abuse disorders or a history of bipolar depression or any psychotic disorder.
- •Are pregnant or lactating; are known to be hypersensitive to sertraline; currently taking an antidepressant medication or seeing a therapist regularly; unable to understand or to complete the questionnaires or to participate in treatment.
研究者
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