跳至主要内容
临床试验/NCT00389246
NCT00389246已完成3 期

Evaluation of Consultation Including Genetic Aspects of Obesity

Philipps University Marburg0 个研究点目标入组 420 人开始时间: 2002年9月1日最近更新:
适应症

试验速览

阶段
3 期
状态
已完成
入组人数
420
主要终点
Self-control

研究概览

简要总结

More than 1,000 obese people are screened for genetic mutations (MC4R). Those with positive screenings as well as 320 randomly selected people without MC4R mutations are randomized to 2 consultation types: one including recommendations for eating and physical activity behavior, the other with an additional part on genetic determinants and actions in obesity. It is hypothesized that obese people with obesity-specific genetic mutations, and obese people with a family history of obesity, benefit more if the consultation includes additional elements on genetic determinants.

详细描述

More than 1,000 obese people are screened for genetic mutations (MC4R). Those with positive screenings as well as 320 randomly selected people without MC4R mutations are randomized to 2 consultation types: one including recommendations for eating and physical activity behavior, the other with an additional part on genetic determinants and actions in obesity. Their results are compared to a control group (n>100). It is hypothesized that obese people with obesity-specific genetic mutations, and obese people with a family history of obesity, benefit more if the consultation includes additional elements on genetic determinants.

The following variables are used: BMI, SCID interview for mental disorders, Stunkard's body silhouttes for participants and their parents and siblings, Restraint Eating Scale, PANAS, Well-being scale, body acceptance, shame and guilt, coping with obesity, participant's satisfaction with consultation.

Assessment Points: before consultation, after consultation, 6 months later.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • BMI > 30

排除标准

  • Brain damage

结局指标

主要结局

Self-control

Feeling guilty for being overweight

Negative affectivity

次要结局

  • weight
  • restraint eating
  • qualityof life
  • body acceptance
  • coping

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Winfried Rief

Professor Dr.

Philipps University Marburg

相似试验