Effect of Aerobic Exercise Training on Ventilatory Efficiency in Patients With Coronary Artery Disease
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 123
- 主要终点
- Ventilatory efficiency in patients with coronary artery disease
研究概览
简要总结
The purpose of the present study was to test the hypothesis that patients with coronary artery disease with lower aerobic fitness exhibit greater responsiveness on improving ventilatory efficiency after aerobic exercise training.
详细描述
Measurements of ventilatory efficiency during cardiorespiratory exercise testing typically expressed as the minute ventilation/ carbon dioxide production ratio have been validated to be useful in assessing the presence and severity of both heart and lung diseases. In this context, previous studies have showed ventilatory inefficiency in patients with coronary artery disease suggests abnormalities in the distribution of ventilation and perfusion in the lungs. In addition, a growing body of studies has demonstrated that lower ventilatory efficiency during exercise is considered an important predictor of risk mortality, hospitalization, and other outcomes than peak VO2.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 48 Years 至 77 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •was stable coronary artery disease diagnosed by coronary angiography
排除标准
- •unstable angina pectoris,
- •complex ventricular arrhythmias,
- •pulmonary congestion and
- •orthopaedic or neurological limitations to exercise
结局指标
主要结局
Ventilatory efficiency in patients with coronary artery disease
时间窗: up to 3 months of the interventions
Measurements of ventilatory efficiency during cardiopulmonary exercise testing typically expressed as the minute ventilation/ carbon dioxide production ratio have been validated to be useful in assessing the presence and severity of both heart and lung diseases. In this context, previous studies have showed ventilatory inefficiency in patients with coronary artery disease suggests abnormalities in the distribution of ventilation and perfusion in the lungs.
次要结局
未报告次要终点
研究者
Danilo Marcelo Leite do Prado
PHD
Hospital TotalCor