Inflammatory and Metabolic Outcomes in Obese Women After 8 Weeks of High Intensity Interval Training and Moderate Intensity Continuous Training: a Randomized Controlled Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 48
- 主要终点
- Inflammatory profile
研究概览
简要总结
The main purpose of this study is to compare the effects of high intensity interval training and moderate intensity continuous training on inflammatory profile and metabolic markers, after 8 weeks of intervention trial in obese women.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
盲法说明
Outcome Assessors involved in data analysis will not be aware of the arm to which the participants were allocated (single-blinded masking)
入排标准
- 年龄范围
- 25 Years 至 41 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Body Mass Index between (30-40 kg/m²)
- •age between 25 and 41 years
- •to be sedentary
排除标准
- •type 1 or type 2 diabetes
- •Hypertension
- •pregnancy, Lactation
- •having undergone bariatric surgery
- •psychological disorders, epilepsy, sever neurological disorders
- •participation in other moderate, vigorous exercise or nutrition intervention
- •acute or chronic cardiovascular disease
- •malignant disease
- •kidney disease
- •lung disease
- •hyperthyroidism or hypothyroidism
- •smoking any type of cigarette
- •joint limitations
- •electronic implants (defibrillator, pacemaker)
研究组 & 干预措施
Control group (CTr)
No counseling or nutritional therapy and no exercise
干预措施: CTR (Other)
Moderate intensity continuous training (MICT)
Follow-up during a period of 8 weeks of supervised ergometer-based moderate-intensity continuous training based on HRmax (MICT).
MICT:
- 3 sessions per week
- intensity at 65-75% HRmax
- time-effort per session: 50 min
干预措施: MICT (Other)
High Intensity Interval Training (HIIT)
Procedures: Follow-up during a period of 8 weeks of supervised ergometer-based high intensity interval training based on HRmax (HIIT).
HIIT:
- 3 sessions per week
- 10 bouts of one minute at 90% HRmax interspersed by one minute at 40% HRmax
- time-effort per session: 25 min
干预措施: HIIT (Other)
结局指标
主要结局
Inflammatory profile
时间窗: 8 weeks (baseline to 8 week follow-up assessment)
C-reactive protein (CRP) (mg/dL)
次要结局
- Cardiorespiratory Fitness (CRF)(8 weeks (baseline to 8 week follow-up assessment) ])
- Lipid profile(8 weeks (baseline to 8 week follow-up assessment) ])
- Blood Pressure (BP)(8 weeks (baseline to 8 week follow-up assessment) ])
- Insulin sensitivity(8 weeks (baseline to 8 week follow-up assessment) ])
- Resting Energy Expenditure (REE)(8 weeks (baseline to 8 week follow-up assessment) ])
- Substrate oxidation rate(8 weeks (baseline to 8 week follow-up assessment) ])
- Body Composition and Anthropometric profile(8 weeks (baseline to 8 week follow-up assessment) ])
研究者
Vivian Marques Miguel Suen
Professor
University of Sao Paulo