Cognitive behavioural therapy for the treatment of late life depression – a multicentre, randomized, observer- blinded, controlled trial (CBTlate) - CBTlate

niversitätsklinikum Köln Klinik für Psychiatrie und Psychotherapie0 个研究点目标入组 248 人开始时间: 2018年6月28日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. out-patient status
•2. male/ female, age = 60 years inclusive at screening
•3. depressive episode (moderate to severe according to ICD-10)
•4. Geriatric Depression Scale (GDS) > 10
•5. Quick Inventory of Depressive Symptomatology (QIDS-C > 10)
•6. MMSE > 25 points
•7. no or stable (= 6 weeks) antidepressive pharmacological treatment at baseline and stable antidepressive pharmacological treatment during 8-week intervention
•8. sufficient German language skills
•9. written informed consent signed

•Bipolar depression
•Schizophrenia
•Other psychotic disorders
•Substance abuse or dependency
•Acute suicidality
•Anxiety disorder as stand-alone diagnosis (e.g. generalized anxiety disorder, panic disorder, phobia)
•Obsessive-compulsive disorder as stand-alone diagnosis
•Participation in another trial of psychotherapeutic/psychiatric intervention parallel to this trial
•Additional psychological/ psychotherapeutic treatment throughout the study including the follow- up visit
•Regular use with scheduled dosing of Benzodiazepines (not PRN)
•Severe or instable medical condition, which clearly impacts on depression or on the ability to participate in the trial
•Brain disease with severe functional impairement that impacts the ability to participate in the trial (e.g. aphasia, Parkinson’s disease)

发起方

niversitätsklinikum Köln Klinik für Psychiatrie und Psychotherapie