NCT03513913Unknown不适用
Comparison of the Effect of Conventional IVF and ICSI Fertilization Method on Human IVF Treatment Outcome
适应症
干预措施
试验速览
- 阶段
- 不适用
- 入组人数
- 600
- 试验地点
- 2
- 主要终点
- Fertilization rate
研究概览
简要总结
In this prospective randomized clinical trial we plan to compare two fertilization method which are widely used during in vitro fertilization (IVF) treatment. Outcome of conventional IVF and intracytoplasmic sperm injection (ICSI) treatment will be compared in this study.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Triple (Participant, Care Provider, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 48 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Infertile patients entering in vitro fertilization treatment At least 1 oocytes collected Semen sample is suitable for IVF and ICSI fertilization as well Number of oocytes collected is lower than 5 AND/OR female age is equal or more than 40 years
排除标准
- •Samen sample is not suitable for conventional IVF fertilization Previous conventional IVF treatment resulted in <50% fertilization rate
研究组 & 干预措施
IVF
Experimental
Oocytes fertilized by conventional in vitro fertilization (IVF) method
干预措施: ICSI (Procedure)
ICSI
Experimental
Oocytes fertilized by intracytoplasmic sperm injection (ICSI) method
干预措施: ICSI (Procedure)
结局指标
主要结局
Fertilization rate
时间窗: 18 hours after insemination
Number of oocytes fertilized
次要结局
- Implantation rate(4 weeks after embryo transfer)
- Clinical pregnancy rate(4 weeks after the embryo transfer)
- Embryo quality(36 and 72 hours after fertilization)
研究者
Peter Fancsovits, Ph.D.
Senior cilincal embryologyst
Semmelweis University
研究点 (2)
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