The criticAl Care nUtrition mulTinational rEgistry
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Oral oral nutrition supplements (ONS) enteral parenteral nutrition support
研究概览
简要总结
Malnutrition is common among critically ill patients and medical nutrition therapy in the form of enteral or parenteral nutrition is therefore considered an integral part of the standard care. While it is accepted that it is unethical to withhold nutrition therapy from those at risk of malnutrition evidence has been generated to demonstrate that various nutrition practices influence clinically important outcomes such as length of stay morbidity and mortality. Older data suggest that providing at least 80 percentage of prescribed amounts of protein and energy is associated with improved clinical outcomes Despite these benefits enteral or parenteral feeding practices themselves are not without adverse effects or risks. Making decisions regarding the most effective and safe means of feeding patients in the ICU can be challenging and consequently considerable variation exists in nutrition practices in this setting. By initiating the Critical Care Nutrition Multinational Registry we aim to describe current nutrition practices in different types of critically ill patients and to monitor changes over time in and between different countries worldwide.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18.00 Year(s) 至 80.00 Year(s)（—）
- 性别
- All
入选标准
- •Expected to be in need of ICU support for an additional 48 hours from screening.This is defined as ongoing organ function support on ICU (eg mechanical ventilation renal replacement therapy, or ongoing inotropic vasopressor support) Receiving any type of nutrition support.
排除标准
- •Expected death or withdrawal of life-sustaining treatments within 7 days from screening Readmitted to the ICU during the study period.
结局指标
主要结局
Oral oral nutrition supplements (ONS) enteral parenteral nutrition support
时间窗: 4 weeks
At each day highest and lowest blood glucose highest lactate hypoglycemic events lowest phosphate
时间窗: 4 weeks
Use of motility agents
时间窗: 4 weeks
次要结局
- Delta Sequential Organ Failure Assessment (SOFA) score(Persistence of Organ Dysfunction (POD) defined as ongoing requirement for vasopressors dialysis or mechanical ventilation at the outcome assessments time points at each ICU day)